Titration of Activated Bovine Factor

نویسنده

  • ROBERT L. SMITH
چکیده

p-Nitrophenyl-p’-guanidinobenzoate is a suitable substrate for the titration of purified bovine Factor X which has been activated by a coagulant protein from Russell’s viper venom. Reaction of Factor Xa with p-nitrophenyl-P’-guanidinobenzoate occurs at the site which is responsible for the clotting activity of Factor Xa. Activation of bovine Factor X by the Russell’s viper venom coagulant protein yields a single active site per 53,000 daltons of zymogen.

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تاریخ انتشار 2002